Located in Chicago's landmark Marina City riverfront complex on North Dearborn, the hotel anchors a revitalized destination that also includes the House of Blues Music Hall and Restaurant and several new attractions. The hotel features 367 rooms and suites, intimate VIP meeting space in the hotel and access to the House of Blues Music Hall and Restaurant for additional meetings and social functions. Special attractions include a 36-lane AMF Bowling Center, a 25,000 square foot Crunch Health Fitness Club, one of Chicago's hottest blues clubs right in the building, and access to a variety of marina activities such as boat rentals.

Created by award-winning interior designer, Cheryl Rowley, the hotel decor incorporates Gothic, Moroccan and East Indian motifs as well as selections from the diverse architectural and artifact collection assembled by the House of Blues and its founder, Isaac Tigrett. Guests will be welcomed into the hotel lobby by large iron cathedral gates opening to ancient blue glass panels from a meditation temple in India, two hand-carved wooden corbels gracing the bar and three colossal male figures circling a large structural column in the center of the lobby. Originally carved in limestone from India, the bodies of the male figures are Indian while the faces are rendered in the style of the southern primitive artist. Each of the guest rooms and suites will display original artwork and utilize the vibrant colors and patterns featured throughout the hotel. The rooms will also be "technology friendly" providing direct internet access via the television, the first hotel in Chicago to offer this feature.

Room rates at the hotel range from $125 for cabin rooms, $175 for standard rooms and $325 for suites. 

House of Blues Hospitality Inc. was created to develop urban hotels in conjunction with House of Blues live music/restaurant venues in exciting locations worldwide. Additional House of Blues venues and/or hotels are targeted for Las Vegas, West Hollywood, New Orleans, New York, Tokyo, Sydney, London and San Francisco. Loews Hotels currently owns and/or operates 14 hotels and resorts in the U.S., Canada and the Principality of Monaco. In the midst of the largest expansion campaign in its history, the chain has a total of six hotels under development. In addition to House of Blues Hotel, a Loews Hotel, these include, the 800-room Loews Miami Beach Hotel (October 1998); the 585-room Loews Philadelphia Hotel (Winter 2000); and the first three on-site hotels at Universal Studios Escape in Orlando. These include the 750-room Portofino Bay Hotel, a Loews Hotel (Spring 1999); a 650-room Hard Rock Hotel (Fall 2000); and a third 1,000-room hotel opening in 2001.